Protein name:
NADPH:adrenodoxin oxidoreductase, mitochondrial (AR;Adrenodoxin reductase) ;
Alternative:
Ferredoxin--NADP(+) reductase (Ferredoxin reductase) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Monomer. Interacts directly with FDX1.
Function:
Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
Subcellular Location:
Mitochondrion matrix
Protein Attributes:
50:
MASRCWRWWG | WSAWPRTRLP | PAGSTPSFCH | HFSTQEKTPQ | ICVVGSGPAG |
100:
FYTAQHLLKH | PQAHVDIYEK | QPVPFGLVRF | GVAPDHPEVK | NVINTFTQTA |
150:
HSGRCAFWGN | VEVGRDVTVP | ELREAYHAVV | LSYGAEDHRA | LEIPGEELPG |
200:
VCSARAFVGW | YNGLPENQEL | EPDLSCDTAV | ILGQGNVALD | VARILLTPPE |
250:
HLERTDITKA | ALGVLRQSRV | KTVWLVGRRG | PLQVAFTIKE | LREMIQLPGA |
300:
RPILDPVDFL | GLQDKIKEVP | RPRKRLTELL | LRTATEKPGP | AEAARQASAS |
350:
RAWGLRFFRS | PQQVLPSPDG | RRAAGVRLAV | TRLEGVDEAT | RAVPTGDMED |
400:
LPCGLVLSSI | GYKSRPVDPS | VPFDSKLGVI | PNVEGRVMDV | PGLYCSGWVK |
450:
RGPTGVIATT | MTDSFLTGQM | LLQDLKAGLL | PSGPRPGYAA | IQALLSSRGV |
491:
RPVSFSDWEK | LDAEEVARGQ | GTGKPREKLV | DPQEMLRLLG | H
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
Polyclonal Antibody for Human AR
Polyclonal Antibody for Human AR
Polyclonal Antibody for Human AR
Polyclonal Antibody for Human AR
Monoclonal Antibody for Human AR
Monoclonal Antibody for Human AR
Monoclonal Antibody for Human AR
Monoclonal Antibody for Human AR
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS SHORT AND LONG);VARIANT GLN-123
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LEU-7; GLN-123; VAL-213; LEU-248; TRP-251; CYS-301; MET-345; SER-352 AND ALA-472
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 4; 5; 6 AND 7);VARIANT GLN-123
tissue :
Adrenal gland .
tissue :
Caudate nucleus .
tissue :
Testis .
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Nature440:1045-1049(2006)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT)
tissue :
Lung .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]